FAQs on Botox Injections for Migraines

Botox injections, popular as wrinkle reducers, are also successful in alleviating pulsing migraine headaches that bothers about one in every 10 Americans. The FDA approved Botox injections in 2010 as a preventive medication for patients experience chronic migraine headache for about 15 days in a month.

How Does Botox Injection Treat Migraine?

Botox injections prevent neurotransmitters responsible for migraine headache. A neurovascular disorder, migraine originates within the brain and spreads with increase in the level of serotonin neurotransmitter. Nerves turn highly sensitive when migraine signals reach the central nervous system and patients experience moderate to severe headaches.

Botox blocks neurotransmitter responsible for carrying nerve impulses and inhibits migraine signals. As these signals cannot reach the CNS, nerves remain normal and patients do not feel the headaches.

How Is Botox Injections for Migraines Administered?

Doctors administer 31 Botox injections to those with migraine problems. The entire dosage and number of injections are distributed across “seven specific areas” on each side of the head, including the forehead, neck, back, temple, and the nasal bridge. The aim is to address and preempt migrane symptoms, such as nausea or vomiting. If the patient has any prime pain location, doctors may increase the number of injections up to 39.

How Many Botox Injections for Migraines Injections Should I Have?

The entire Botox migraine treatment plan spreads over a period of 60 weeks with patients treated with injection once in 12 weeks.

Patients feel pain relief within 10 to 15 days of the injections. The American Headache Society recommends additional injections if there is no significant relief with the first set.

What Are Exclusive Benefits of Botox Injections for Migraines?

Botox injections provides up to three months relief for migraine patients. Used as a preventive medication, the treatment put a stop to pulsating painful symptoms ensuring improved quality of life. It reduces both frequency and intensity of migraine attacks by inhibiting trigger points.

When Patients Require Botox Injections for Migraines? What Conditions Are Treated Through Botox Injections for Migraines?

According to the FDA, Botox migraine injections are for adults aged between 18 and 65 years and with migraine pain experienced more than 14 days a month.

What Are The Side Effects of Botox Injections for Migraines?

Botox injections provide a good way to avert and inhibit migraine headaches. However, like other procedures, these injections may lead to certain side effects. Stiffness and pain in the neck is common among patients treated with Botox injections. Many experience a bubble effect and temporary muscle weakness.

Many experience flu-like symptoms after having Botox injections. Contact your doctor if you have vision changes, hives, or severe allergy after the procedure.

May I Combine Other Treatments With Botox Injections for Migraines?

Yes, you can have other conservative therapies or oral medications for migraines simultaneously with Botox injections.

How L Does It Take?

It takes about 10 to 15 minutes for a Botox injection procedure.

Do I Need Rest After Botox Injections?

You can go home and join your daily routine. It is better if you take rest, as small bumps appearing on your forehead may cause headache for a few hours.

How Well Does Botox Injections for Migraines Work? What Are The Benefits of Botox Injections for Migraines?

  • In 2011, scholars at the University of Granada Institute for Neuroscience found that Botox injections administered twice with a gap of three months considerably reduces “frequency, intensity, and scale of migraine attacks” with “mild and temporary side effects.”
  • The Migraine Association of Ireland conducted a trial involving over 1,300 patients and discovered that Botox injections provided considerable benefit compared to placebo treatments without any major side effects. Those administered Botox injections had fewer migraine days, over 50 percent reduction in frequency of attacks, and better quality of life.


University of Granada. “Botox injected in head ‘trigger point’ shown to reduce migraine crises.” ScienceDaily. ScienceDaily, 12 May 2011.

Hidalgo J, Rodríguez-López CM, García-Leiva JM, Rico-Villademoros F, Calandre EP. Effectiviness botulinum toxin type A in the prophylaxis of severe and treatment–refractory migraine. Journal of Headache and Pain, 2006; 7 (S-1): S-18